Plantar keratoderma of Sézary syndrome
نویسنده
چکیده
Sézary syndrome is an extremely rare form of cutaneous T-cell lymphoma. It presents suddenly and is associated with a poor prognosis. Clinical recognition is crucial for the diagnostic process and initiation of appropriate treatment. Plantar keratoderma is usually pathognomonic for Sézary syndrome and clinicians should be alerted to its presence.
منابع مشابه
Rothmund-Thomson syndrome. The first case with plantar keratoderma and the second with coeliac disease.
We report two unusual patients with Rothmund-Thomson syndrome (RTS), a rare genodermatosis. The first patient is a 5-year-old girl with congenital poikiloderma, photosensitivity, plantar punctate keratoderma, stunted growth and severe mental retardation. Plantar keratoderma associated with RTS has been reported only once. The second patient is a 21-year-old female presenting with rounded "moon"...
متن کاملAn Unusual Dermatological Side Effect of Treatment with Non-Pegylated Alpha-Interferon, Acitretin and Puva Therapy: Pigmented Macules on the Fingers in a Patient with Sézary Syndrome
Sézary syndrome is a cutaneous T-cell lymphoma characterized by the triad of erythroderma, generalized lymphadenopathy, and the presence of Sézary cells in skin, lymph nodes and peripheral blood. A 59-year-old Chinese female presented with erythroderma, palmoplantar keratoderma and enlarged right axillary and epitrochlear lymph nodes. Staging investigations showed extensive involvement of perip...
متن کاملPseudoherpetic keratitis. Corneal changes in circumscribed palmo-plantar keratoderma.
The association of herpetoid corneal changes with circumscribed palmo-plantar keratoderma was first described by Richner (I938). Hanhart (1947) suggested that this represented a recessively inherited ectodermal syndrome, and the condition is sometimes called the Richner-Hanhart syndrome. Subsequent reports have been relatively few: Cremona (I 957); Kuske (I959); Franceschetti and Thier (I96I); ...
متن کاملHelen Ollendorff Curth and Curth-Macklin Syndrome
Helen Ollendorff Curth (1899-1982), is one of the pioneers in dermatology. In 1954, she and Madge Thurlow Macklin (1893–1962), an American medical geneticist, reported, a rare congenital genodermatosis that was later known as Curth-Macklin syndrome. This syndrome is a rare autosomal dominant skin disorder characterized by extensive hyperkeratosis and palmo-plantar keratoderma. This report shed ...
متن کاملHaim Munk syndrome: report of two siblings of northern India treated with acitretin.
Haim Munk Syndrome (HMS) is the allelic mutation of exon 6 codon in cathepsin C gene. Here, we present two cases of same family with HMS having all the cardinal features of HMS which includes palmo plantar keratoderma and periodontitis along with arachnodactyly, acroosteolysis, onychogryphosis, and marked osteopenia on hand wrist radiographs. Both the siblings were treated with cotrimoxazole, a...
متن کامل